About Phentermine: its advantages, precautions, how to take, results of therapy.

Phentermine is a relative of methamphetamine which acts upon the neural system, causing the release of dopamine, adrenalin and noradrenalin into the brain. The drugs also acts upon the central nervous system, resulting in a decrease in appetite and working in much the same way as phendimetrazine, another commonly used appetite-suppressant. Simply put, the drug causes the generation of adrenalin which sends the body into 'fight or flight' mode and cutting off the hunger signal before it reaches the brain.

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Phentermine was approved by the FDA as an appetite-suppressant in 1959, and has since been released on to the market under a variety of trade names. It is currently sold as Ionamin, Adipex-P and Phentermine. As with other weight loss drugs which are chemically related to amphetamine, the drug is available only on prescription and is regarded under US Controlled Substances Act as a controlled substance. It is in the nature of these drugs that long-term use can result in chemical addiction and, as such, Phentermine should be taken as a short-term measure only.

SmithKline Beecham's brand of phentermine, Fastin, was removed from the market in 1996; and a compound of phentermine and fenfluramine or dexfenfluramine was removed from the market the following year, after studies showed that the drug dramatically increased the risk of heart valve disease.

Phentermine itself, however, is still regarded as safe and effective by the FDA; and there is no evidence to suggest dangerous side-effects. Phentermine hydrochloride has been widely available since the 70s, and has proven a dramatically effective, short-term weight loss aid.

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